Evaluation of human pulp tissue response following direct pulp capping with a self-etching adhesive system containing MDPB

This study evaluated the human pulp tissue response following direct capping with Clearfil Protect Bond (CPB) self-etching adhesive containing an antibacterial monomer MDPB. The pulps of third molar teeth were exposed by removal carious tissue. In experimental group, CPB was applied to and dentin. control groups, SE (CSE) or calcium hydroxide-based cement (CH) surfaces. All filled resin composite, extracted after 90 days, responses histologically analyzed. No severe inflammation soft disorganization observed in CH groups. CSE group exhibited a disorganized odontoblastic layer inflammatory infiltration. hard formation formed more than CPB. induced acceptable healing when directly bacterial contamination.